Mekin Duo contains a patented micro-encapsulated source of all-trans-MK-7 vitamin K2 (K2VITAL), obtained through a particular process which, compared to the common fermentative process, guarantees greater requirements in terms of stability and purity. 7-trans pure. This stereoisomerism is very important as it is the only one that ensures the correct interaction with the enzymes at the cell membrane level, guaranteeing the desired biological effect. Vitamin K2 in the form of menaquinone-7 promotes the incorporation of calcium into the bone matrix through the activation of osteocalcin, preventing calcium deposits in the soft tissues and arteries.

Ingrediants
Magnesium bisglycinate; outer shell: hydroxypropylmethylcellulose; vitamin K2 (menaquinone-7), vitamin B2 (riboflavin), stabilizers: calcium phosphates; anti-caking agents: silicon dioxide, magnesium salts of fatty acids.

Gluten -free and lactose -free.

Nutritional characteristics

Average values per daily dose (1 capsule)
Vitamin K2 (Menaquinone)	110 mcg (113% NRV *)
Vitamin B2	1.2 mg (80% NRV *)
Magnesium	56.25 mg (15% NRV *)

How to use
Take one capsule a day after the main meal.
However, it is advisable to consult a doctor.

Warnings
Supplements are not intended as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of the reach of children under three years of age. Do not take in case of hypersensitivity or allergies to one or more components. For pregnant and lactating women it is recommended to seek medical advice.

storage
Store in a cool and dry place, at a temperature not exceeding 25 ° -30 ° C, away from light and / or heat sources. The minimum conservation term refers to the product correctly stored in an unopened package.
Validity for intact packaging: 36 months.

Format
Pack of 30 vegetarian capsules of 500 mg.
Net weight: 15 g.

Bibliography
LJ Schurgers, C. Vermeer (2000) Determination of phylloquinone and menaquinones infood. Effect of food matrix on circulating vitamin K concentrations Haemostasis 30298-307
P. Szulc, MC Chapuy, PJ Meunier, PD Delmas (1993) Serumundercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women JClin Invest 91 (4) 1769- 1774.
MHJ Knapen, NE Drummen, E. Smit, C. Vermeer, E. Theuwissen (2013) Three-yearlow-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausalwomen Osteoporosis Int 24 (9) 2499-2507.
K. Pucaj, H. Rasmussen, M. Moller, T. Preston (2011) Safety and toxicological evaluation of a synthetic vitamin K2, menaquinone-7Toxicol Mech Methods 21 (7) 520-532.
E. Theuwissen, EC Cranenburg, MH Knapen et al (2012) Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects Br J Nutr 31 1-6.