Alpiflor

Gastropiu 'Pro

Dietary supplement

Food supplement with patented formula.
The ingredients can be useful for those who, for various reasons, need help to maintain the correct balance of gastric and esophageal mucosa homeostasis.
The association of the ingredients is patented as thanks to this formulation the formation of the alginate polymer and the hyaluronic acid gel takes place simultaneously thus allowing the rapid incorporation of the alginate polymer inside the hyaluronic acid gel even before the alginate polymer precipitates internal acid content of the stomach.

Information on ingredients derived from international literature
Hyaluronic acid : hyaluronic acid is one of the fundamental components of the connectivity of man and mammals. Its concentration in the tissues of the body tends to decrease with advancing age. Chemically it can be defined as a non-sulphured and protein core-free unglycosaminoglycan, from the non-branched polysaccharide chain produced by the condensation of thousands of disaccharide units formed in turn by residues of hyaluronic acid and N-acetylglucosamine linked between them, alternatively, by glycosidic bonds 131 -> 4 and 31 -> 3, as well as by intramolecular hydrogen bonds, which stabilize its conformations. At physiological pH the carboxylic groups of the glucuronic units are ionized, giving the hyaluronate high polarity, and consequently a high solubility in water. Thanks to this property, hyaluronate is able to complex with many water molecules reaching a high degree of hydration, forming a gel. Hyaluronic acid also plays an important role in tissue repair and protection.
Under normal conditions, proteoglycans in the ground substance of the connective tissue mucosa represent an effective barrier against bacterial invasion and spread. If this barrier is damaged, the topical application of molecular weight hyaluronic acid, thanks to its macro-aggregating effect on protein glycans, can favor their reconstruction. The macro-aggregate effect of hyaluronic acid on proteoglycans inhibits the formation of edema. During the initial phase of inflammation, hyaluronic acid is secreted by the body as a natural response of the tissue against the damaging action of bacterial hyaluronidases and the formation of edema. Hyaluronic acid has therefore been used as an anti-inflammatory, anedemigenic and protective agent of the gastric and laryngo-esophageal mucosa (1).
Sodium alginate : alginates are neutral polysaccharide polymers isolated from brown algae (Phacophycae) and are classified as dietary fiber. They consist of a percentage of D-mannan L-glucuronic acids. In the presence of gastric acid, glialginates precipitate to form a gel, which tends to form a floating barrier on the mouth of the stomach (2). Clinical studies have shown that the pH of the alginate barrier is neutral, while the gastric pH below the barrier is decidedly acidic (2). These studies show that with the presence of dialginates an effective barrier is formed against gastric acidity; also show that there is a rapid reduction of symptoms related to esophageal reflux (3, 4). Recent studies have confirmed the efficacy of alginates in reducing symptoms associated with esophageal reflux (5).

How to use
We recommend taking one sachet after meals as needed, even the night before bedtime.

Warnings
Do not exceed the recommended daily dose

Format
Keep out of the reach of children under 3 years of age. The supplements are not intended as a substitute for a varied and balanced diet and a healthy lifestyle.
Pack of 20 sachets of 1 g