Diosven Plus

Diosmin 300mg

Dietary supplement

Inflammatory edema processes in the medical and surgical fields.

Contraindications / Side Effects

Hypersensitivity to the active substance or to any of the excipients; the product is contraindicated in patients with haemophilia and haemorrhagic diathesis as in the case of severe liver and kidney disease; peptic ulcer; due to the presence of lactose among the excipients, patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption, should not take this medicine; due to the presence of sucrose among the excipients, patients with rare hereditary problems of fructose intolerance, glucose / galactose malabsorption or sucrase-isolactase insufficiency, should not take this medicine.

Dosage

Adults: the optimal dosage of attack and '1 coated tablet, four times'. 1 tablet coated 2-3 times a day as maintenance therapy. The coated tablets should be swallowed whole, preferably on an empty stomach. Children: experience on the use of the product in children is limited; until sufficient data on safety and efficacy are acquired, the use of the drug is to be reserved for adults.

Warnings

In pregnant women and in infancy use only in case of real need. Experience on the use of the drug in children is limited; until sufficient data on safety and efficacy are acquired, the use of the drug is to be reserved for adults. It is advisable to check the coagulation indices in patients with haemophilia and haemorrhagic diathesis. Bromelain should be used with particular caution in patients with severe liver disease or renal insufficiency. The possible appearance of manifestations of hypersensitivity of various types and locations suggests the interruption of the treatment and the institution of a suitable therapy. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption should not take this medicine. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomatase insufficiency should not take this medicine.

Interactions

The association of the drug with anticoagulants often requires an adequate adjustment of the dosage.

Side effects

Cases of nausea, vomiting, diarrhea and, rarely, cases of menorrhagia and metrorrhagia have been reported. Occasionally, skin allergic situations, erythema, itching and in rare cases asthma attacks may occur. Gastrointestinal disorders. Common: nausea, vomiting, diarrhea. Respiratory, thoracic and mediastinal disorders. Rare: asthmatic attack. Skin and subcutaneous tissue disorders. Rare: allergic skin reaction, erythema, itching. Reproductive system and breast disorders. Rare: menorrhagia, metrorrhagia. The reporting of suspected adverse reactions that occur after the authorization of the drug is important, as it allows continuous monitoring of the benefit / risk ratio of the drug.

Pregnancy and breastfeeding

For bromelain, no clinical data on exposed pregnancies are available. Studies on animals (rats and rabbits) did not show embryotoxic or teratogenic effects. Therefore, the medicine should be administered during pregnancy and lactation only in case of real need '.