Healavis

Intra-Articular Syringe

Administration induces a normalization of the viscoelasticity of the synovial fluid and an activation of the tissue repair processes at the level of the articular cartilage.
In some experimental models an anti-inflammatory and analgesic activity of hyaluronic acid was also highlighted. These properties translate into an improvement in joint function and a control of the objective and subjective symptoms related to arthrosis disease.
Exogenous hyaluronic acid, being a substance widely present in the body, is physiologically metabolized after parenteral administration by integrating into the common metabolic pathways of hexoses.
The results of the studies carried out intra-articularly in dogs and rabbits, after single and repeated administration, indicate that hyaluronic acid is rapidly distributed in the joint tissues and remains there for a long time: the marked product is in fact found in the synovial membrane already 2 hours after administration and remains there for up to 7 days; the maximum concentration of marked hyaluronic acid is found in the synovial fluid and then, decreasing, in the joint capsule, in the ligaments and in the adjacent muscle.
In some experimental models an anti-inflammatory and analgesic activity of hyaluronic acid was also highlighted. These properties translate into an improvement in joint function and a control of the objective and subjective symptoms related to arthrosis disease.