Melatonin Zinc Selenium Pierpaoli® 60 Tablets

Melatonin Zinc Selenium Pierpaoli® - Food Supplement

Why this formulation?

Original formula born from the scientific observations matured during fifty years of research and clinical studies conducted by Prof. Walter Pierpaoli and his collaborators, on Melatonin and on the relationship between the structures of the central nervous system (hypothalamus-pituitary-pineal gland ) and the endocrine and immune systems.

Pierpaoli® Zinc-Selenium Melatonin is a suitable formulation of immediate-release Melatonin, which, taken at bedtime, reducing the time required to fall asleep, helps to keep the body synchronized with the physiological cycle of the body to regulate biological sleep-wake rhythm.

Not just for sleeping

Pierpaoli ® Zinc-Selenium Melatonin is characteristic among the supplements in the sleep area for having an exclusive original formulation, based on fifty years of scientific and clinical research by Walter Pierpaoli and collaborators on the relationship between the structures of the neuro-endocrine system ( pineal-hypothalamus-pituitary gland) and the immune system. It is a supplement also studied to contribute to a beneficial effect for the normal physiological functions of the immunobiological system. It specifically combines 3 active ingredients: Melatonin, synthesized in humans by the pineal gland which is the fundamental organ in maintaining the body's biological balance, associated with Zinc and Selenium for the normal function of the immune system.

Sleep, immune defenses and protection from oxidative stress

Melatonin Zinc Selenium Pierpaoli® is an original formula that in addition to promoting sleep quality, helps to support the immune system, combining the advantages of: Melatonin, which contributes to the reduction of time to fall asleep, Zinc and Selenium, which contribute to protection of cells from oxidative stress and the normal function of the immune system

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What is Melatonin and why is it important?

Melatonin is a natural molecule synthesized mainly by the Pineal gland, which regulates the synthesis and cyclic secretion of the body's hormones and is responsible for the nocturnal melatonic peak.

The nighttime Melatonin spike initiates a sequence of effects that keep the body synchronized with the physiological cyclicality of hormones and cells. It is during childhood that the production of Melatonin reaches its maximum, then it begins to gradually decline until it flattens out and disappears in old age.

Melatonin is synthesized by the pineal gland which is the organ that plays an important role in the regulation of biological cycles and circadian rhythms (chronobiological functions) and as such helps to regulate the main physiological processes including the sleep-wake cycle.

Scientific evidence shows that supplementation with Melatonin can help in certain cases of alteration of normal circadian rhythms and sleep disturbances, including those caused by jet lag, alteration of normal sleep-wake rhythms.

Melatonin has been shown to be effective especially for

• Help restore the body's natural biological rhythms and alleviate the effects of some circadian rhythm disorders (circadian dysrhythmia)
• Contribute to the reduction of the latency of sleep onset
• Assist in restoring the chronobiological alignment of sleep with the internal biological clock

Indications

Melatonin Pierpaoli contributes to the reduction of the time required to fall asleep; the beneficial effect is obtained by taking 1 mg of Melatonin just before going to sleep.

Melatonin helps alleviate the effects of jet lag.

Zinc contributes to the normal function of the immune system and to the protection of cells from oxidative stress.

Selenium contributes to the protection of cells from oxidative stress and to normal thyroid function.

Original formula born from the scientific observations gained during fifty years of research and clinical studies conducted by Prof. Walter Pierpaoli and his collaborators, on Melatonin and on the Pineal gland, and on their close relationship with the mechanisms of aging.

Pierpaoli Melatonin Zinc Selenium was developed with the aim of obtaining a peak release of Melatonin during the night and was formulated to meet the needs of the body's physiological functions.

Formulation developed on the basis of clinical studies.

Composition

Melatonin, Zinc gluconate, Selenium and Mannitol.

How to use

We recommend taking 1 tablet of Melatonin Zinc Selenium Pierpaoli® in the evening half an hour before going to bed, and in any case preferably between 22.00 and 00.00.

Warnings

Do not exceed the recommended daily dose. Supplements are not intended as a substitute for a varied, balanced diet and a healthy lifestyle. Keep out of reach of children under three years, do not take during pregnancy, store below 25 ° C and protect from light. Excessive use can cause laxative effects due to the presence of mannitol.

Safety information

Using Melatonin in recommended dosages is safe. Taken according to the indications, Melatonin is generally well tolerated and free from particular side effects.
Numerous scientific publications and studies confirm the safety of Melatonin.

Even at high doses, the medical-scientific literature proves the good tolerance of melatonin, with only mild adverse effects which in type and frequency are similar to those found in placebo.
Pierpaoli® Melatonin Zinc Selenium is not addictive or addictive. By interrupting the administration of exogenous Melatonin, the Pineal gland resumes synthesizing the endogenous molecule in physiological quantities.

It is advisable to always consult your doctor beforehand if

• You are being treated with drugs to make sure there are no contraindications or the possibility of interactions;
• The use is intended for children and women during breastfeeding;
• They take supplements for prolonged periods or "chronically".

Given the lack of studies in this regard, the intake of Melatonin should be avoided during pregnancy.

Prolonged use

The use of Melatonin has been shown to be safe in the short and medium term (3-18 months), even at doses higher than those indicated, and more and more studies and clinical data prove the safety of long-term intake.

However, as a precaution, we recommend that you inform your doctor if you use it for prolonged periods or continuously.

Format

Pack of 60 tablets.